Anti-Diarrhoeal Activity of Blighia sapida (Sapindaceae) in Rats and Mice
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چکیده
منابع مشابه
Anti-diarrhoeal activity of a polyherbal formulation in rats and elucidation of its cellular mechanisms
Objective: The present study was aimed to study anti-diarrhoeal activity of a polyherbal formulation (PHF) in rats and elucidate its mechanism of action. Materials and Methods: Anti-diarrhoeal activity of PHF was investigated using castor oil-induced diarrhoea, small intestinal transit and enteropooling models in rats. PHF was tested at 75, 150 and 300 mg...
متن کاملChanges in Lipid Profile of Aqueous and Ethanolic Extract of Blighia sapida in Rats
Aqueous and ethanolic leaf extracts of Blighia sapida was assessed for some lipid profile parameters in normal albino rats. Daily administration of the extracts (50 and 100 mg/kg body weight) for 21days showed that the extract significantly (p<0.05) reduced the levels of total cholesterol, triglycerides and LDL-cholesterol in all the treated groups w hen compared with the control. While signifi...
متن کاملAcute - Toxicity, Anti-Inflammatory and Anti-Diarrhoeal Activity of Ailanthus excelsa in Mice and Rats
Ailanthus excelsa (Stem bark) are used in folk medicine for a treatment of inflammation, arthritis, expectorant, stimulant and asthma. Acute toxicity study of A. excelsa stem bark was performed on mice (Swiss) and albino rats (Wistar strain),given single doses 1,10, 50, 100 ,1000 and 2000mg/kg,po. showed normal behavior and no mortality up to 14 days except 500,1000 and 2000mg/kg dose 20%, 60.0...
متن کاملEvaluation of Bronchodilator and Anti-Anaphylactic Activity of Myrica sapida
Background: Asthma is a chronic inflammatory disorder of the airways. The available treatment options have major limitations owing to low efficacy, associated adverse events and compliance issues. Therefore, the health burden of bronchial asthma is increasing globally at an alarming rate, providing a strong impetus for the development of new therapeutics. Myrica sapida is known traditionally in...
متن کاملEthanol Extract of Blighia sapida Stem Bark Show Remarkable Prophylactic Activity in Experimental Plasmodium berghei–Infected Mice
This work explores the antiplasmodial potential of ethanol extract of Blighia sapida (Lin. Sapindaceae) in chloroquine (CQ)-resistant Plasmodium berghei (ANKA strain)-infected mice. Chloroquine-resistant (ANKA) strain of P berghei was inoculated intraperitoneally into Swiss albino mice. Mice were treated orally for 4 consecutive days, before and after inoculation (prophylactic, suppressive, and...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Toxicology
سال: 2009
ISSN: 1816-496X
DOI: 10.3923/jpt.2009.117.125